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MDs and Big Pharma

October 20th, 2010 Comments off

Unsurprising but still disturbing: Drug companies pay 17,000 U.S. doctors, report finds. See the ProPublica database Doctors for Dollars (cited in the news story) for more details on the data compiled on drug company payments to MDs.

Industry Influence

October 18th, 2010 Comments off

Two interesting news stories…

Pfizer Attacks Journal For Undisclosed Conflicts
In an interesting turn on the more traditional story of academic journals charging Big Pharma with COI, in this case Pfizer is charging PloS Medicine with not disclosing a COI on one of its recent publications. In this case, as in so many, the Devil is in the Details.

Big Oil goes to college: a conflict of interest?
A more conventional story about institutional COI and the lengths to which some industries will go to encourage research that is favourable to their commercial agendas (and discourage other areas of work)…and the failure on the part of institutions to take seriously the influence that such investments can have on independent science.

Examiners and Grad Students

October 18th, 2010 Comments off

As I’ve commented on before in this blog, the world of academia is the site of many interesting and challenging conflicts of interests (COI) that go beyond financial interests. And in many cases, the COI results not from individual misbehaviour, but because of institutional realities that create situations where people unavoidably have multiple and potentially conflicting interests.

A case in point is the issue of how we evaluate graduate theses. When students submit a Masters or PhD thesis for evaluation, it is common to require external, i.e., impartial, examiners of various sorts (e.g., external to department, or to university) to review the thesis and ensure that the review process is fair and meets widely shared academic standards. But as noted in this commentary by Yves Laberge in UniversityAffairs — How external is your external examiner? — “It was easier to draw the line between “internal” and “external” examiners before the 1980s, when collaboration between faculties at different uni­versities was less common.

In an era of national and international collaboration, alongside increasing hyperspecialization of research fields, it is likely that the people best placed to review a graduate student’s thesis have also collaborated with the supervisor and/or student. Academics are busy people, and organising a review committee is a time consuming process. Often, we have to call in favours to get colleagues to review student theses or sit on exam committees. And there is little (if any!) funding with which to bring in physically external colleagues to participate in an exam, although video conferencing helps somewhat (but has its own limitations).

Now there are clearly policies and practices in place to reduce the risk or harm of bias (e.g., excluding collaborators from committees), but these often rely on a simple distinction between “internal” and “external” evaluators. And they may also undermine the review process, when for example, external reviewers are non-specialists in the student’s area of study, because the student and supervisor have worked with most of the specialists!

As Laberge concludes,

One thing is certain: it is easier to point out emerging problems than to suggest efficient solutions.

In my opinion, universities need to redefine the status of the “insider” and the status of the “external examiner,” to acknowledge the new kinds of networking relationships that have developed in the last three decades. These issues need to be addressed and debated, and not only by deans.

The bottom line is that a colleague who works on the same research project as the can didate and thesis supervisor but comes from another university should not in any instance be considered an “external examiner.” To maintain the validity of their thesis and the value of their degree, future PhD candidates should face a real jury that is not too familiar with their work nor onside in advance.

COI news round-up

September 28th, 2010 Comments off

After a busy summer (but with some vacation), and an extremely busy September with the beginning of the academic term, I’ve finally found time to catch up on COI news. The following are some stories that caught my attention recently:

Universities and Interests

Industry and Science

Medicine and Pharma

COI Conference – Tunisia

July 23rd, 2010 Comments off
24 – 25 Septembre 2010
Hôtel Accropole – Les Berges du Lac – Tunis